Malegra FXT Plus should not be used with nitrate medications (such as nitroglycerin) or certain other antidepressants without medical supervision, as it may cause dangerous interactions, including low blood pressure or serotonin-related side effects. A PDE5 inhibitor that increases blood flow to the penis during sexual stimulation. It helps achieve and maintain an erection by enhancing the nitric oxide–cGMP pathway. A selective serotonin reuptake inhibitor (SSRI) that increases serotonin levels in the brain.
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